DSLD Samples Needed
Updated: Dec 22, 2020
Exciting news - EtalonDx is expanding a large genetic study for Degenerative Suspensory Ligament Desmitis (DSLD) in the horse, and we need your help! Samples are needed from horses diagnosed with DSLD. DNA samples will be accepted Monday, December 21, 2020 - January 20, 2021 from affected horses.
To participate in this clinical study, please provide the following:
1) Veterinary diagnosis of Degenerative Suspensory Ligament Desmitis, which limbs are affected, how long the horse has been symptomatic (X-Rays, Ultrasound, or written confirmation from vet accepted)
2) Mail in a pulled hair sample (tail hairs with root bulb preferred, mane hairs also acceptable) or whole blood, tissue biopsy, etc.
3) Horse name, age, height, gender (include in "additional information" under your horse's profile, or email information to us at firstname.lastname@example.org)
4) Full photos of horse standing (upload conformation photo online to your horse's profile under "gallery photos", or email them to us at email@example.com)
5) Any available videos (including video of movement, radiographs, or ultrasounds)
Degenerative Suspensory Ligament Desmitis (DSLD) is a disease that affects the connective tissue of the lower limbs in many horses. We are honing in on Sporthorses such as Thoroughbreds and Warmbloods for this particular study. Horses with DSLD usually present with a history of lameness, heat or swelling in the fetlocks, enlarged fetlocks, and gradual dropping of the fetlocks towards the ground.
Additional signs of DSLD include:
Pasterns may appear horizontal during weight-bearing (see image)
Pain on palpation of suspensory ligament and/or flexor tendons
Varying degrees of lameness
Stumbling and tripping
Digging holes and standing with toes pointing toward hole
Hindlimb conformation may change to post-legged stance
Change in gait such as weight shifting, landing toe first, or stiff robot-like movement
Lying down frequently and not wanting to rise (sometimes misinterpreted as colic)
Instability in gait or when standing that can be misdiagnosed as neurologic disease
Because the onset of this disease can be subtle, it is critical that all samples sent into Etalon's lab are from horses with a veterinarian's diagnosis for DSLD.
To submit samples, visit www.etalondx.com and click “order”. Create an online profile and click “Order Testing”.
Choose package “STUDY_DSLD” to send in your sample free of charge. Those whose samples are included in the study will receive follow-up information for results and publications.
Mail hair samples to:
405 El Camino Real, #234 Menlo Park, CA 94025
Please know how much we appreciate your participation in genetic research as we try to decode the various equine diseases including DSLD. With your help, together we can continue to improve the lives of our horses and the equestrian community as a whole.
firstname.lastname@example.org (650) 380-2995